Chemistry and Pharmacological Action of Thymus Vulgaris L.: A Review
Uma Srivastava,
Navneet Kumar Verma,
Prashant Singh ,
Pragya Mishra,
Shweta Yadav,
Satya Prakash Singh,
Dr. Ahamefula Anslem Ahuchaogu
Pages 16 - 20
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Abstract
Thyme's high concentration of bioactive chemicals and ethnopharmacological significance make it one of the most significant therapeutic herbs. The alternative natural antioxidant and antibacterial thyme, which has potential applications in the food business, is the main topic of this review. This is in keeping with the tastes of the modern customer, who seeks for natural and healthy items. Thyme is a desirable natural additive because various studies have shown that using it prolongs the shelf-life of foods (meat, meat products, milk, fish, or seafood products) and decreases lipid oxidation. In contrast to other natural preservative extracts, thymus extracts and essential oils are used less frequently as natural food additives despite these findings. Taking into consideration the source of the thyme (plants, plant extracts, or essential oils), this study offers a summary of the most significant research on the beneficial effects of the plant's bioactive constituents and its applications as a food preservative.
Original Article
Open Access
Applications of Nanoparticles In Biology
Navneet Kumar Verma,
Asheesh Kumar Singh,
Mo. Arshad Raza,
Jitender Chaurasiya,
Kundan Kumar,
Uma Srivastava
Pages 11 - 15
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Abstract
At the forefront of the quickly evolving discipline of nanotechnology are nanomaterials. These materials are outstanding and indispensable in many areas of human activity because of their special size-dependent characteristics. This concise overview aims to provide an overview of the latest advancements in the field of applied nanomaterials, including their use in biology and medicine, and addresses the potential for commercialization. Because of their customisable surface properties and large range of core materials, nanoparticles are a great platform for a wide range of biological and medicinal applications. An overview of nanoparticle–biomolecular interactions and current uses of nanoparticles in biological sensing, delivery, and imaging of living cells and tissues are given in this review.
Original Article
Open Access
Artificial Intelligence In Machine Learning
Navneet Kumar Verma,
Asheesh Kumar Singh,
Abhishek Singh,
Ashok Yadav,
Uma Srivastava
Pages 8 - 10
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Abstract
One of the most fascinating developments in artificial intelligence in recent years is machine learning. Understanding algorithms for a variety of everyday applications. One of the reasons a learning algorithm one that is employed by Google or Microsoft works so effectively every time an online search engine like Google or Bing is used to search the internet is because it has learnt how to rank web sites. The SCOPUS database and Web of Science were used for the analysis. Moreover, N Vivo 12 and UCINET software were utilised to finish them. In order to show how the field has changed from 1999 to the present, a study of the literature on ML and AI empirical investigations produced in the past century was done. Eighty-two articles underwent classification and evaluation. The first noteworthy outcome is the higher volume of American-published publications and the growing interest following the introduction of Industry 4.0.
Original Article
Open Access
Efficacy Comparison of Transversus Abdominis Plane Block with Levobupivacaine Versus Combined Levobupivacaine and Dexmedetomidine for Postoperative Analgesia in Cesarean Delivery
Divyashri C,
Aman Varshney,
Bhavya Periyadka
Pages 1 - 7
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Abstract
Background: Effective postoperative pain management in cesarean delivery is crucial for patient recovery and satisfaction. This study aimed to evaluate the efficacy of transversus abdominis plane (TAP) block with levobupivacaine versus a combination of levobupivacaine with dexmedetomidine for postoperative analgesia in cesarean delivery.
Methods: In this double-blinded randomized control trial, 90 patients undergoing cesarean delivery under spinal anesthesia were divided into three groups: Group C (control), Group L (levobupivacaine), and Group LD (levobupivacaine with dexmedetomidine). The primary outcome was the time to the first request for rescue analgesia. Secondary outcomes included pain scores at rest and on movement, patient satisfaction, and the incidence of side effects.
Results: The time to first request for rescue analgesia was significantly longer in Group LD (600 minutes) compared to Group L (352.5 minutes) and Group C (90 minutes) (p<0.05). Pain scores at rest and on movement were lowest in Group LD at all time intervals, with significant differences observed when compared to both Group L and Group C (p<0.05). Patient satisfaction was highest in Group LD. The incidence of side effects such as nausea and pruritus was comparable across all groups.
Conclusion: The addition of dexmedetomidine to levobupivacaine in TAP blocks significantly enhances postoperative analgesia in cesarean delivery, with prolonged pain relief and higher patient satisfaction without increasing side effects. These findings support the use of dexmedetomidine as an adjunct in TAP blocks for improved pain management post-cesarean delivery.
IASR Journal of Medical and Pharmaceutical Science